Let's take a minute to talk about your medication. This is Endari. It helps reduce the complications of sickle cell disease. It may have other uses, too. It is often taken twice a day, at the same time each day. You should take it exactly as your doctor tells you to. Endari comes as a powder and each dose should be mixed with a full 8 oz glass of a beverage, such as water, milk or apple juice. It can also be mixed with food, such as applesauce or yogurt. It is important to note that each packet contains 5 grams of medication. You should read the 'Instructions for Use' for full information. If you still have questions, your doctor or pharmacist can help. Most people tolerate this medicine well. Common side effects include constipation, nausea, or headache. These effects are normal if they are mild and should go away. Some people can also have a cough or pain in the stomach, chest, back, arms or legs. You should talk to your healthcare provider about which symptoms to watch for and when to report them. If these or other side effects become reasons you want to stop taking this medicine, please talk to your doctor or pharmacist. You should not stop taking this medicine unless your doctor says it's okay. To help keep this medicine safe for you, your doctor will follow your condition closely. It is not known if this medication can harm unborn babies. So, women should check with their doctors before becoming pregnant and before breastfeeding. For best results with Endari, continue taking it as directed, and follow your doctor's advice about ways to help with your condition.