Let's take a minute to talk about your medication. This is mupirocin ointment 2%, and you should apply a thin layer onto the affected skin as directed by your doctor. Your doctor will also advise if you should cover the area with a sterile bandage or other wound dressing. You should wash your hands thoroughly before and after applying it. Mupirocin ointment is an antibiotic for the skin, and is used to cure certain skin infections. It is very well tolerated. Still, let your doctor know if you notice any unusual changes to the area, like skin irritation, itching, rash or stinging that does not go away. Mupirocin ointment is only safe for use on the skin, so be careful not to get it in your eyes. If you don't see any improvement after three to five days, or if at any time your skin looks worse, please call your doctor right away. Also, it is important to know that you shouldn't use it longer than prescribed, because this could actually cause an additional infection. For best results, continue using mupirocin ointment for the amount of time your doctor prescribed, and don't skip doses.